Name: Megan Sambrook
Lab Group: Roper Group, School of Life Sciences
Email Address: M.Sambrook@warwick.ac.uk
Previous Academic Background
Gained a Interdisciplinary Biomedical Science Masters (MSc), with Distinction, from the University of Warwick as part of the MRC DTP Program. I completed two 10 week projects in the following areas:
Studying the activity of monofunctional glycosyltransferases with respect to antibacterial resistance, under the supervision of Professor David Roper.
Synthesising pH-responsive cyclic peptide nanotubes for biological targets, under the supervision of Professor Sebastien Perrier.
I graduated from the University of Surrey with a first class Biomedical Science (Bsc) degree and completed my final year project in the lab of Dr Kevin Maringer; investigating the interactions between arboviruses and the mosquito immune system. My project involved characterising mosquito cells with CRIPSR knock-outs of genes involved in the RNAi immune pathway, to ultimately investigate the role of RNAi in viral persistence.
During my undergraduate, I spent a year in Dr Arleen Rifkind's lab (Weill Cornell Medical College, NY, USA) where I studied the effects of the environmental toxin, 2, 3, 7, 8 - tetrachlorodibenzo-p-dioxin (TCDD) on hepatocellular gene expression.
I also worked part time at the Surrey Clinical Research Centre, a phase I, human clinical trials unit where I had a variety of responsibilities assisting the clinical, laboratory, project management and sleep research team in running vaccination and sleep studies.
PhD at Warwick
I am currently working in Professor David Roper's Lab, studying the molecular basis for enhanced cephalosporin resistance in Vancomycin Resistant Enterococci (VRE).